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Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy.
Van Damme H, Dombrecht B, Kiss M, Roose H, Allen E, Van Overmeire E, Kancheva D, Martens L, Murgaski A, Bardet PMR, Blancke G, Jans M, Bolli E, Martins MS, Elkrim Y, Dooley J, Boon L, Schwarze JK, Tacke F, Movahedi K, Vandamme N, Neyns B, Ocak S, Scheyltjens I, Vereecke L, Nana FA, Merchiers P, Laoui D, Van Ginderachter JA. Van Damme H, et al. J Immunother Cancer. 2021 Feb;9(2):e001749. doi: 10.1136/jitc-2020-001749. J Immunother Cancer. 2021. PMID: 33589525 Free PMC article.
The role of hepatic macrophages in liver metastasis.
Keirsse J, Van Damme H, Geeraerts X, Beschin A, Raes G, Van Ginderachter JA. Keirsse J, et al. Among authors: van damme h. Cell Immunol. 2018 Aug;330:202-215. doi: 10.1016/j.cellimm.2018.03.010. Epub 2018 Apr 6. Cell Immunol. 2018. PMID: 29661474 Review.
Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages.
Murgaski A, Kiss M, Van Damme H, Kancheva D, Vanmeerbeek I, Keirsse J, Hadadi E, Brughmans J, Arnouk SM, Hamouda AEI, Debraekeleer A, Bosteels V, Elkrim Y, Boon L, Hoves S, Vandamme N, Deschoemaeker S, Janssens S, Garg AD, Vande Velde G, Schmittnaegel M, Ries CH, Laoui D. Murgaski A, et al. Among authors: van damme h. Cancer Res. 2022 Oct 17;82(20):3785-3801. doi: 10.1158/0008-5472.CAN-22-0094. Cancer Res. 2022. PMID: 35979635 Free PMC article.
Beyond the M-CSF receptor - novel therapeutic targets in tumor-associated macrophages.
Bonelli S, Geeraerts X, Bolli E, Keirsse J, Kiss M, Pombo Antunes AR, Van Damme H, De Vlaminck K, Movahedi K, Laoui D, Raes G, Van Ginderachter JA. Bonelli S, et al. Among authors: van damme h. FEBS J. 2018 Feb;285(4):777-787. doi: 10.1111/febs.14202. Epub 2017 Sep 6. FEBS J. 2018. PMID: 28834216 Free article. Review.
Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment.
Kiss M, Lebegge E, Murgaski A, Van Damme H, Kancheva D, Brughmans J, Scheyltjens I, Talebi A, Awad RM, Elkrim Y, Bardet PMR, Arnouk SM, Goyvaerts C, Swinnen J, Nana FA, Van Ginderachter JA, Laoui D. Kiss M, et al. Among authors: van damme h. Front Immunol. 2022 Dec 1;13:1003975. doi: 10.3389/fimmu.2022.1003975. eCollection 2022. Front Immunol. 2022. PMID: 36531986 Free PMC article.
IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D.
Kiss M, Vande Walle L, Saavedra PHV, Lebegge E, Van Damme H, Murgaski A, Qian J, Ehling M, Pretto S, Bolli E, Keirsse J, Bardet PMR, Arnouk SM, Elkrim Y, Schmoetten M, Brughmans J, Debraekeleer A, Fossoul A, Boon L, Raes G, van Loo G, Lambrechts D, Mazzone M, Beschin A, Wullaert A, Lamkanfi M, Van Ginderachter JA, Laoui D. Kiss M, et al. Among authors: van damme h. Cancer Immunol Res. 2021 Mar;9(3):309-323. doi: 10.1158/2326-6066.CIR-20-0431. Epub 2020 Dec 23. Cancer Immunol Res. 2021. PMID: 33361087
Transcutaneous Vagal Nerve Stimulation Alone or in Combination With Radiotherapy Stimulates Lung Tumor Infiltrating Lymphocytes But Fails to Suppress Tumor Growth.
Reijmen E, De Mey S, Van Damme H, De Ridder K, Gevaert T, De Blay E, Bouwens L, Collen C, Decoster L, De Couck M, Laoui D, De Grève J, De Ridder M, Gidron Y, Goyvaerts C. Reijmen E, et al. Among authors: van damme h. Front Immunol. 2021 Dec 1;12:772555. doi: 10.3389/fimmu.2021.772555. eCollection 2021. Front Immunol. 2021. PMID: 34925341 Free PMC article. Clinical Trial.